Test Code: 201
CPT Code(s): 80329
Includes: Acetaminophen
Methodology: Immunoturbidimeteric, Enzymatic
Clinical Significance: Acetaminophen is an analgesic/anti-inflammatory agent that may be hepatotoxic when ingested in quatities exceeding 150mg/kg.
Additional names: Acet; Tylenol; Acetm
Supply: Supply #T64 Red Serum (NO GEL) 6mL
Preferred Specimen: Serum
Preferred Volume: 2mL
Transport Container: Red Top Tube (NO GEL)
Transport Temperature: Refrigerated
Specimen Stability: Refrigerated: 2 days
Rejection Criteria: EDTA plasma is not acceptable; Specimens with hemolysis greater than 2+ will be rejected and should be recollected.
- Hemolysis
- What are hemolyzed specimens?
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Hemolysis occurs when the red cells are damaged during sample collection causing them to rupture. Hemolyzed serum or plasma is pale pink to red rather than the normal clear straw or pale-yellow color.

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- What causes a specimen to be hemolyzed?
- Mixing tubes too vigorously
- Placing tubes in the refrigerator without allowing 30 minutes at room temperature for complete clotting
- Exposure to heat or in a refrigerator that is too cold
- Using a needle with too small of a bore necessary for the venipuncture
- Using too large a tube when using a butterfly needle
- Not allowing sufficient time for alcohol to dry on puncture site
- Leaving the tourniquet on for longer than one minute
- How can hemolyzed specimens be prevented?
- For routine collections, use a 20–22-gauge needle
- Do not remove the needle from the vein with the vacuum tube engaged
- Do not collect a specimen in a hematoma
- Do not centrifuge the specimen for a prolonged period of time
- Draw the sample gently and evenly
- What are hemolyzed specimens?
Special Instructions: Hemolyzed, icteric, and lipemic samples should not be used.
For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.